Top Sector LSH stimulates, facilitates and finances a variety of Public-Private Partnerships (PPPs) to realise its central mission “five more years of healthy living and reducing socioeconomic health differences by 30%”. A PPP is a national multi-year, thematic and programmatic collaboration between quadruple helix organisations that contribute to at least one of the five missions from the societal theme Health & Care. There are currently about 40 strategic, thematic, long-term collaborations within large, national consortia. Based on their societal relevance, scientific quality and economic potential, Top Sector LSH will support and facilitate these strategic PPPs via specialised information sessions and matchmaking meetings to enable maximal knowledge exchange.