Developing an interactive App for high-density mapping of disease complaints

Many chronic diseases, especially rare ones, are not wel-characterised with regard to their day-to-day burden of disease in terms of symptoms and health related quality of life. Neither do we have a clear grasp of environmental and life style factors that may influence the level of complaints. This has in part to do with their infrequent occurrence, but also to the fact that we lack accurate tools to measure the severity of symptoms and patterns over time, be it diurnal of weekly. To overcome this shortcomings, we intend to develop together with a commercial partner an innovative App, that will be able to capture different complaints and factors such as timing of medication, ambient conditions, etc. Participants will receive push messages prompting them to respond within a short time frame to a few concise questions such as level of itch, fatigue, or pain and “at what time did

you take your last medication?”. These questions will be issued randomly a few times per week, enabling us to collate a high density mapping of complaints and potential influencing factors. This tool will yield a wealth of information and may prove useful for predicting disease flares and for validation of symptom scores. At the end of the day, by making the tool more generic, it will be applicable for both research questions and patient care in many diseases. 

The project has yielded a fully operational App, which is marketed by EveryhereIM  under the name “Moniq”. With this App we have completed and published a successful research project titled: “Symptom patterns in the daily life of PSC patients (Liver International 2022).