Killing latently infected cells to cure HIV

Induced cell death for HIV cure

In this innovative project led by the Erasmus MC's Viroscience Department, a new public-private partnership has been established to tackle the complex challenge of HIV. This collaboration aims to delve deeper into understanding and treating this persistent virus. 

HIV remains a significant global health concern, with millions affected worldwide. Its impact extends beyond health, affecting societies and economies. Current treatments can manage the virus but not cure it, highlighting the need for innovative solutions. This project addresses this gap, focusing on the hidden HIV reservoirs in the body, which are key obstacles in curing HIV. 

The approach involved developing precise laboratory techniques to detect these hidden HIV reservoirs and testing various therapies to target and eliminate them. This strategy could revolutionize HIV treatment, offering new avenues to combat the virus more effectively. 

The project's deliverables included advanced methods to detect latent HIV reservoirs and innovative treatment strategies. These developments are significant steps towards a potential cure for HIV, aiming to effectively target and eradicate the virus from its hidden reservoirs. 

Summary
Advanced HIV research, including creating assays to detect latent HIV reservoirs and investigating therapies to target and eliminate these reservoirs effectively. We also explore novel methods to activate immune responses against HIV-infected cells.
Technology Readiness Level (TRL)
4
Time period
48 months
Partners