Top Sector Life Sciences & Health (LSH) entails a broad scope of disciplines, from pharmaceuticals to medical technology and from healthcare infrastructure to vaccination. To realise its mission – vital citizens in a healthy economy - the Top Sector builds on the strengths of the Dutch LSH sector to address the biggest societal challenges in prevention, cure and care. By funding multidisciplinary public-private partnerships (PPPs) the Top Sector aims to facilitate innovation. Here we give an overview of  a number of funded R&D projects by Top Sector LSH. The page is updated continuously.

An ultra-small two-colour fluorescence microscope for intravital imaging

Two-colour Intravital Miniscope (T-CIM)

Fluorescence microscopy finds wide application in the health and life sciences, but fluorescence microscopes are often bulky and expensive. This consortium will develop a portable low-cost intravital fluorescence microscope tailored for regenerative medicine, neuroscience or cancer research. The development of the miniature two-colour fluorescence imager will be catalysed by partnering with Everix Optical filters and the 4th Physics institute at the University of Stuttgart.

By creating a low-cost portable microscope for two-colour fluorescence imaging, the technology becomes accessible to scientists on a tight budget, or those that would like to scale up their research in a cost-effective manner. Moreover, the miniature microscopes will facilitate intravital imaging of tumour growth, tissue regeneration or prevalent neurological conditions in animal disease models. This should significantly advance research and find cures for numerous diseases that have both a large economic and societal impact.