Projects

Top Sector Life Sciences & Health (LSH) entails a broad scope of disciplines, from pharmaceuticals to medical technology and from healthcare infrastructure to vaccination. To realise its mission – vital citizens in a healthy economy - the Top Sector builds on the strengths of the Dutch LSH sector to address the biggest societal challenges in prevention, cure and care. By funding multidisciplinary public private partnerships (PPPs) the Top Sector aims to facilitate innovation. Here we give an overview of funded R&D projects by Top Sector LSH.

Microbial strain quality for industrial application

Industry makes extensive use of gene banks and microbial collections. The largest and qualitatively the best fungal collection in the world is housed at the Westerdijk Institute (CBS) in Utrecht, with a holding of ≈100,000 living strains. Some strains are originals dating back from the 19th century, the early days of microbiology. Obviously strains have to be re-investigated with modern techniques before they can successfully be applied.

In this project we focus on species with possible health implications as well as a potency for bioremediation in collaboration with our industrial partners Thermo Fisher Scientific and Dae Kwang Chemical.

The project will be basal to the development of innovative techniques for identification, and provide safe material to be used in bioremediation of oil-polluted sites and cleaning of industrial exhaust via biofiltration. Results will be used for the public database ‘Atlas of Clinical Fungi’, where classical strain data are augmented with data of modern techniques, and antifungal susceptibility data for direct clinical use.