A live attenuated vaccine against coronaviruses: virological characterization of a challenge virus strain
Development of a live attenuated vaccine against a deathly coronavirus in cats
This application builds on the previously granted TKI LSH project entitled “Construction of a toolbox of enabling technology for coronavirus vaccine strategies”. It involved the construction and testing of a novel type of live attenuated vaccine against coronaviruses.
Coronaviruses are well-known for their zoonotic potential and for their ability to cause deadly infections in humans (SARS-coronavirus, MERS-coronavirus etc.) as well as in animals, and for which no vaccines are yet available. Because testing of vaccine efficacy against such lethal viruses in humans is ethically not feasible, the approach was to develop a prototype vaccine against a lethal animal coronavirus, feline infectious peritonitis virus (FIPV).
Infections by FIPV result in severe systemic disease that is almost invariably fatal. It is the most dreaded infection among cat owners as there are no preventive or therapeutic measures. It is the aim to develop a vaccine against FIPV.
In this project, a FIPV challenge virus will be tested and characterised that will be used in future vaccination-challenge experiments.
Other projects
In each PPP project, research institutions, businesses and healthcare organisations work together on a specific health challenge. Browse the full project overview.
Bekijk de programma’s
Binnen onze programma’s werken bedrijven, kennisinstellingen en regionale partners samen aan innovaties die bijdragen aan betere gezondheid en zorg.
Bekijk de partnerschappen
Strategische publiek-private partnerschappen (PPP's) zijn meerjarige samenwerkingen tussen bedrijven, kennisinstellingen en andere partijen.
Hoe kunnen we je helpen?
Heb je een vraag of wil je meer weten over Health Holland? We brengen je graag in contact met de juiste mensen, kennis en mogelijkheden om gezondheidsinnovatie te versnellen.
We have received your message
We will contact you within 3 to 4 working days. If your question is urgent, please contact us directly. Below is the contact option that best matches your subject.
Start again
Something went wrong while sending the form. Please try again.