1073 Projecten
Using nanoparticles to repair genes in blood stem cells
NANOCAST 1 and 2, in which Erasmus MC, LUMC and Harbour Antibodies join forces, aims to develop an efficient delivery method for the systemic administration of CRISPR genome editing components to blood stem cells
Targeting blood vessels to treat dementia
Novel derivatives of Thalidomide complemented with ultrasound imaging technologies to treat dementia
Engineering clotting factor X for therapeutic purposes
Engineering variants of blood coagulation factor X for the prevention and treatment of bleeding
Improving upon conventional chest radiography diagnostics
Improving on routine chest radiography; AI meets ULDCT to boost healthcare quality and access
Demonstrating chondroprotective, anti-inflammatory, and analgesic activity of IL4-10FP in osteoarthritis
Synerkine Pharma’s IL4-10FP is potentially the first drug that meets the criteria of a DMOAD
Polymer injection for treatment and prevention of endoleaks
Gaining insight into a novel polymer injection technique and bringing it closer to clinical practice
Screening of drug efficacy utilizing human atherosclerotic data
Our data point to a novel categorization of atherosclerotic human plaques that will be extremely relevant for patient stratification in drug studies. Five plaque types were discovered that reveal different underlying biology and expression of drug responsive genes.
Stem cell models for personalized treatment of rare genetic diseases
Better drug development for rare diseases through disease models that match drugs and responding patients.
Radiological workflow for diagnostic and treatment decisions in multiple sclerosis
Our novel workflow allows neurologists to use quantitative imaging measurements when treating individual
patients
patients