The Follow The Dot project evaluates the use of Virtual Reality in EMDR (VR-based EMDR) in children with post-traumatic stress symptoms in a multicenter Randomized Controlled Trial (RCT). VR-based EMDR stimulates self-care in the family setting and is expected to reduce symptom recurrence, enhance patient satisfaction and improve quality of life.
The project LIF2.0 aims to develop a short term response to COVID-19 needs in industry and public organisations by offering a real time COVID-19 driven data platform covering European wide aggregated content from a vast amount of sources. Users will have insights for developing new echo period strategies.
This project aims to unravel mechanisms underlying beneficial effects of a novel food supplement on cognitive performance. This may contribute to the prevention of cognitive impairment and ultimately dementia. Focus will be on adults with an emerging pre-mild cognitive impairment condition who will benefit most from evidence-based intervention and prevention strategies.
Replacing current invasive testing by a simple blood test to enable prenatal diagnosis for pregnant couples carrying severe monogenic diseases, is much desired. In this project the aim is to develop an efficient NIPD method for monogenic diseases, for implementation in the clinic.
The aim is to improve vaccines by including viral innate immune antagonists that are co-expressed with the antigen to boost vaccine efficacy.
A fully automated microscopy and image analyses pipeline was developed for cultured human neurons. The findings show that human neurons with a molecular alteration that is specific for frontotemporal dementia show changes in connectivity that may be an important early causal factor in the disease.
Ex-COVID-19 patients will undergo medical tests and biological samples will be analysed to increase the understanding of who is at risk for chronic disease. The influence of environmental factors and of a lifestyle intervention will be analysed, and lab research will contribute to better mechanistic insights providing leads for interventions.
This proposal aims at developing a simple and fast diagnostic method for SARS-CoV-2, aiming at efficient and large-scale testing in society. Cellulose-based virus capturing is combined with two methods for detection: isothermal amplification (RT-LAMP), and ultrafast PCR and used for Point-of-Care testing.
Viral pneumonias (eg. COVID-19) have unpredictable disease courses and can be extremely severe because of tissue damage induced by the virus or hyperactivation of the host immune system. The point-of-care (SEH) 24/7 fully automated flow analysis allows fast immune profiling to monitor deterioration of disease on the ward and ICU.
Addition of glycerol esters of short chain fatty acid (eSCFA) to pig feed has beneficial health effects and can thereby reduce the use of antibiotics in the farming industry. This project investigates which specific antimicrobial peptides are upregulated by eSCFA and determines how these peptides add to the health benefit.