Electrocardiogram analysis for early detection of cardiovascular diseases in COVID-19 patients

COVID-19 is a new phenomenon which has both a respiratory and a cardiac impact regarding the health of the patient. Rapid detection of the cardiovascular abnormalities in a COVID-19 patient will support treatment decisions. In this project a new rapid method will be developed to detect these cardiovascular characteristics in COVID-19 patients by only using non-invasive 12-lead ECG data.

Transmission scanning for accurate magnetic resonance positron emission tomography

Photon attenuation correction methods for PET-MRI are currently developed using CT transmission images obtained prior to the PET-MRI scan. Their accuracy is limited by differences due to patient movement. A transmission scan mechanism will be integrated into the PET-MRI system, capable of acquiring transmission images simultaneously during the PET-MRI scan.

Improving hyperthermia for more efficient cancer therapy

Hyperthermia is an adjuvant treatment to locally heat tumors (40-44oC) making chemotherapy and radiotherapy significantly more effective without adding side-effects. The following will be developed: estimation, optimisation and control methods to heat tissue accurately, fast and non-invasively using on-line adaptations based on 3D MR-temperature maps (“closing the loop between MR and heating application by automatic control).

Combining Optics and Acoustics for Realtime Guidance during Cancer Surgery

It is proposed to develop a technology for real time guidance during cancer surgery. A probe will be developed that informs the surgeon realtime on the tissue type underneath the instrument. This will be achieved by strategically combining ultrasound imaging with the accurate tissue sensing capabilities of optical spectroscopy within one handheld device.