Top Sector Life Sciences & Health (LSH) entails a broad scope of disciplines, from pharmaceuticals to medical technology and from healthcare infrastructure to vaccination. To realise its mission – vital citizens in a healthy economy - the Top Sector builds on the strengths of the Dutch LSH sector to address the biggest societal challenges in prevention, cure and care. By funding multidisciplinary public-private partnerships (PPPs) the Top Sector aims to facilitate innovation. Here we give an overview of  a number of funded R&D projects by Top Sector LSH. The page is updated continuously.

34 projects

  • Hyper-glycosylation of Anti-Citrullinated Peptide Autoantibodies in Rheumatoid Arthritis

    The correlation between the effectiveness of RA treatment with the level of ACPA glycosylation.
  • Linking VASculopathy and Fibrosis with Autoimmunity in Systemic Sclerosis

    This project aims to unravel the link between vasculopathy and autoimmunity and, eventually, fibrosis in systemic sclerosis.
  • How do dendritic cells help tumor-killing T cells?

    How do CD4 T-cells and dendritic cells educate cytotoxic T-cells, key weapons in cancer immunotherapy?
  • Quantitative in vivo imaging of heart failure

    This project will yield quantitative imaging technologies for early detection of cardiac diseases.
  • The common disease mechanisms of immune mediated inflammatory diseases

    Uncovering common disease mechanisms of T-cell driven immune mediated inflammatory diseases to enable precision medicine.
  • Recognising renal cancer in urine

    The development of urinary biomarkers will enable improved detection and risk-stratification for renal cell carcinoma.
  • TOFA-Predict in psoriatic arthritis patients

    TOFA-Predict utilizes an unprecedented systems medicine approach to find molecular fingerprints predicting response to therapy in patients with psoriatic arthritis.