How changes in lung tissue structure drive fibrotic lung disease
Exploring novel strategies for reversing tissue imprinting of macrophages in fibrotic lung disease
630 projects
Does inhaled anticholinergic treatment improve airway inflammation in asthma?
PANTANI study to investigate anti-inflammatory effects of Glycopyrronium in asthma
Establish a well-functioning prehabilitation clinic led by properly educated multi-disciplinary teams
The prehab clinic for a structured way of pre-operative assessment and optimisation of the patient
Finding drugs to prevent organ failure during sepsis
Sepsis patients can develop multiple organ failure. Here, new drugable vascular targets will be studied
Platelet preserving effects of Aprotinin
Aprotinin reduces blood loss in cardiac surgery, but the mode of action is incompletely understood
Molecular drivers of Chronic Mucus Hypersecretion in COPD
RNA-seq and bacterial 16S rRNA-seq to identify molecular and microbiome drivers of Chronic Mucus Hypersecretion in COPD
Clinical trial comparing immunosuppresion and the effects on kidney function in Lung transplantation (REVOLUTION trial)
Preserving kidney function in lung transplantation patients by changing immunosuppression
Site selective chemotherapeutic releasing vehicles for controlled delivery
A selective approach with use of nanoparticles is investigated to reduce side effects and increase effectiveness of chemotherapy
A study of genome-wide gene expression in single cells to investigate spontaneous asthma remission
High-throughput, high resolution single cell transcriptomic profiling of the immune and epithelial cell populations in the airway wall provides insights into the cellular immune pathways
Why and in which COPD patient might nocturnal non-invasive ventilation be effective?
This study investigates if NIV stabilises the lung function via beneficial effects on inflammation and repair pathways