Health-Holland

PPP Allowance Top Sector Life Sciences & Health supports innovative research carried out by public- private partnerships (PPPs) in the Dutch LSH sector. Stakeholders from research organisations, health foundations and companies (start-ups, SMEs and industry) are invited to jointly invest in R&D to perform groundbreaking innovations and to contribute to a strong and sustainable LSH sector that plays a major role in finding solutions for healthcare challenges around the world. With the PPP (Public-Private Partnership) Allowance, the Top Sector provides stakeholders, such as research organisations, knowledge institutes, companies, and health foundations with a financial tool to realise their innovative ideas. Partnerships are offered the opportunity to apply for a PPP Allowance twice a year and can receive funding for up to 75 % of the R&D costs provided that both the company and the research organization, make a substantial contribution in cash and/or in kind to jointly bear the costs and risks of the R&D project. The Top Sector Life Sciences & Health ‘Health~Holland’, matches every euro invested by private partners with up to 30 cents by the Dutch government. The Top Sector LSH currently finances 27 projects in the field of biopharma with a PPP Allowance. Unraveling the genetic basis of ALS by large-scale genetic Innovation Credit The Dutch Ministry of Economic Affairs & Climate Policy offers Innovation Credit in the form of a risk-bearing loan that companies can use in the (technical) development phase of a product, process or service that is considered ‘technically new’. Funding, which can also be applied to the development of medical products that require a clinical study, varies from 25% for large companies to 45% for SMEs. This can be applied to project costs capped at 10 million euros with a minimum project size of 150,000 euros. Any additional expenses must be financed from the company’s own resources. Companies must repay the loan within ten years after the settlement date. This requirement may be waived if the project fails for technical reasons or if there is a change in the commercial environment. During the development phase, interest is added to the loan; generally at 7% for technical development projects and 10% for clinical development projects. Businesses can only apply for the credit if they lack sufficient resources to finance their project. Both SMEs and large companies whose activities are based in the Netherlands can apply for a loan for their projects, which must have a maximum duration of four years. Applicants must have a systematic development approach and a detailed project plan. sequencing is currently one of the projects financed with a PPP Allowance. MIT Scheme The MIT Scheme (SME Innovation Stimulation) offers SME entrepreneurs the opportunity to receive additional funding for innovative R&D activities within the Top Sector. The funding, partly from national and regional instruments, can be used in several ways: knowledge vouchers, innovation consultancy projects, feasibility projects and R&D joint ventures. Knowledge vouchers: An SME entrepreneur can present a knowledge voucher to a centre of expertise for a scientific inquiry into a research question. Innovation consultancy projects: To obtain innovation advice and recommendations from a centre of expertise or independent consultancy, such as answering a research question or addressing a request for advice. Feasibility projects: To identify the potential technical and financial risks of a proposed innovation project. R&D joint venture: A collaboration with at least one other SME entrepreneur to innovate or develop a product, production process or service. Innovation-oriented schemes 66

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